British Air Force Typhoon jets have joined forces with French aircraft in a combined operation targeting an hidden munitions depot in Syria operated by the IS group, as stated by the UK's MoD.
The site, pinpointed through surveillance, was assessed as containing munitions and bombs, the statement said, and was situated in mountains just to the north of the ancient city of Palmyra in central Syria.
"The RAF jets used laser-guided Paveway IV weapons to strike a several entry passages providing entry to the depot... initial indications indicate the target was engaged successfully," officials stated.
There was no evidence of any harm to civilians in the operation on Saturday evening and each participating jet returned safely, the defence officials confirmed.
The British jets were backed up by a Voyager refuelling tanker.
The Islamic State group - also known as Daesh - enforced extremist governance over large swathes of both Syria and Iraq prior to its 2019 collapse.
"This strike underscores the UK's leading role, and resolve to operate in unison with our partners, to eradicate any revival of Daesh and their violent and radical beliefs in the area," the British Defence Secretary the Defence Secretary remarked.
RAF aircraft have performed overwatch operations over Syria to "forestall any attempted resurgence" of IS after its defeat at the climactic battle in Baghuz in the year 2019, the MoD reported.
"I extend gratitude to every member of British forces who took part in this mission for their expertise and their bravery," Healey said. "They were part of thousands of British personnel stationed over the festive period. This action, to take out dangerous terrorists who threaten our safety, highlights how British military are ready to step up, continuously, keeping Britain secure within its borders and strong abroad."
In December, the American forces carried out what it described as a "massive strike" targeting IS targets in Syria, after an attack killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations says Islamic State still maintains roughly 5-7 thousand fighters in Iraq and Syria.